Dr. Graham Ruby is currently a Principal Investigator at Calico Life Sciences. His lab applies quantitative genetic and demographic analyses to describe the aging process and discover its genetic foundations in humans and model organisms. His research activities include genetic association studies, deep phenotyping with the use of artificial intelligence and genome annotation using “-omics” data sets. As a postdoc with Dr. Joseph DeRisi at UCSF, Graham wrote software (PRICE) for the discovery of novel viruses from metagenomic deep-sequencing of clinical specimens. As a graduate student with Dr. David Bartel at MIT, he analyzed deep-sequence data for the annotation and characterization of microRNA genes.